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Article

Intracellular gonadotropin-releasing hormone receptors in breast cancer and gonadotrope lineage cells.

The Journal of endocrinology - 1 Dec 2006

Sedgley Kathleen R, Finch Ann R, Caunt Christopher J, McArdle Craig A

Abstract excerpt

Gonadotropin-releasing hormone receptors (GnRHRs) are expressed in gonadotropes and several extra-pituitary sites. They are assumed to be cell surface proteins but the human (h) GnRHR lacks features favoring plasma membrane localization and receptor location varies with cell type. When expressed in mammary (MCF7) cells, cell surface hGnRHR binding was much lower than that of mouse and sheep GnRHRs (type I GnRHRs...

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Identifiers

PMID: 17170220
DOI: 10.1677/joe.1.07067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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