Article
Neurogenesis decreases during brain maturation from adolescence to adulthood.
Pharmacology, biochemistry, and behavior - 1 Feb 2007
He Jun, Crews Fulton T
Abstract excerpt
Adolescence is an important stage of brain development. Recent studies have indicated that neurogenesis in the brain occurs throughout life prompting comparisons of adolescent and adult neurogenesis. Since insulin-like growth factor 1 (IGF-1) has been implicated in promoting neurogenesis we investigated the levels of neurogenesis in adolescents (PND30) and adults (PND120) using IGF-1 over-expressing mice and...
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