Article
Genome-wide scan of additional Jewish families confirms linkage of a myopia susceptibility locus to chromosome 22q12.
Molecular vision - 4 Dec 2006
Stambolian Dwight, Ibay Grace, Reider Lauren, Dana Debra, Moy Chris, Schlifka Melissa, Holmes Taura N, Ciner Elise, Bailey-Wilson Joan E
Abstract excerpt
PURPOSE: A genome-wide scan was previously reported for myopia in Ashkenazi Jews. In order to confirm the previous linkage peaks, a collection of DNA samples from 19 new Ashkenazi Jewish families were tested for linkage in a genome wide scan. METHODS: Families were ascertained from an Orthodox Ashkenazi Jewish community through mailings. Myopia was defined as equal to or greater than -1 diopter in both meridians...
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