Article
Candidate high myopia loci on chromosomes 18p and 12q do not play a major role in susceptibility to common myopia.
BMC medical genetics - 3 Aug 2004
Ibay Grace, Doan Betty, Reider Lauren, Dana Debra, Schlifka Melissa, Hu Heping, Holmes Taura, O'Neill Jennifer, Owens Robert, Ciner Elise, Bailey-Wilson Joan E, Stambolian Dwight
Abstract excerpt
BACKGROUND: To determine whether previously reported loci predisposing to nonsyndromic high myopia show linkage to common myopia in pedigrees from two ethnic groups: Ashkenazi Jewish and Amish. We hypothesized that these high myopia loci might exhibit allelic heterogeneity and be responsible for moderate /mild or common myopia. METHODS: Cycloplegic and manifest refraction were performed on 38 Jewish and 40 Amish...
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