Article
Regulation of lymphokine-activated killer activity in T-replete and T-cell-depleted human bone marrow by interleukin 4.
Experimental hematology - 1 Oct 1991
Drobyski W R, LeFever A V, Truitt R L
Abstract excerpt
Donor-derived lymphokine-activated killer (LAK) cells appear to play a role in mediating an antileukemia effect in recipients of both T-replete and T-cell-depleted (TCD) bone marrow transplants. LAK activity, however, is subject to regulation by cytokines other than interleukin 2 (IL-2). The purp...
Topics
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- Bone Marrow
- Bone Marrow Cells
- CD3 Complex
- CD56 Antigen
- Cell Adhesion
- Cell Separation
- Dose-Response Relationship, Drug
- Down-Regulation
- Humans
- Interleukin-2
- Interleukin-4
- Killer Cells, Lymphokine-Activated
- Lymphocyte Activation
- Phenotype
- Receptors, Antigen, T-Cell
- Recombinant Proteins