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Article

Nitric oxide release is impaired in hypertensive individuals with familial history of stroke.

American journal of hypertension - 1 Dec 2006

Cosentino Francesco, Francia Pietro, Musumeci Beatrice, De Siati Luca, Rao Maria Assunta, De Luca Nicola, Balla Cristina, De Sensi Francesco, Volpe Massimo

Abstract excerpt

BACKGROUND: A genetic origin of cerebrovascular accidents has long been suspected on the basis of epidemiologic evidence and familial aggregation. Nevertheless, the final phenotype is largely influenced by concomitant risk factors. We aimed to investigate whether impairment of endothelium-dependent vasodilation can be used as an informative intermediate vascular phenotype in hypertensive patients with familial...

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Source

Identifiers

PMID: 17161765
DOI: 10.1016/j.amjhyper.2006.06.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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