Article
CTX-M: changing the face of ESBLs in Europe.
The Journal of antimicrobial chemotherapy - 1 Feb 2007
Livermore David M, Canton Rafael, Gniadkowski Marek, Nordmann Patrice, Rossolini Gian Maria, Arlet Guillaume, Ayala Juan, Coque Teresa M, Kern-Zdanowicz Izabela, Luzzaro Francesco, Poirel Laurent, Woodford Neil
Abstract excerpt
Since around 2000 - earlier in Poland and Spain and later in France and the UK - dramatic shifts have occurred in the prevalence and types of extended-spectrum beta-lactamases (ESBLs) in Europe. Before this watershed, most producers were nosocomial isolates, often Klebsiella spp. or Enterobacter spp. from specialist care units, and had mutant TEM or SHV ESBLs. Subsequently, CTX-M ESBLs have become dominant, with...
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