Article
Global epidemiology of CTX-M β-lactamases: temporal and geographical shifts in genotype.
The Journal of antimicrobial chemotherapy - 1 Aug 2017
Bevan Edward R, Jones Annie M, Hawkey Peter M
Abstract excerpt
Globally, rates of ESBL-producing Enterobacteriaceae are rising. We undertook a literature review, and present the temporal trends in blaCTX-M epidemiology, showing that blaCTX-M-15 and blaCTX-M-14 have displaced other genotypes in many parts of the world. Explanations for these changes can be attributed to: (i) horizontal gene transfer (HGT) of plasmids; (ii) successful Escherichia coli clones; (iii) ESBLs in...
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