Article
Influence of candidate susceptibility genes on tuberculosis in a high endemic region.
Molecular immunology - 1 Mar 2007
Søborg Christian, Andersen Aase Bengaard, Range Nyagosya, Malenganisho Wabyahe, Friis Henrik, Magnussen Pascal, Temu Mansuet M, Changalucha John, Madsen Hans O, Garred Peter
Abstract excerpt
Genetic susceptibility towards clinical tuberculosis has been proposed in several population studies. We investigated whether polymorphisms in the candidate genes encoding solute carrier 11a1 protein (SLC11A1 formerly NRAMP1), mannose-binding lectin (MBL2) and Vitamin D receptor (VDR) were associated with tuberculosis in an East-African setting. Four hundred and forty-three culture positive pulmonary tuberculosis...
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