Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-environment interactions in the development of combined type ADHD: evidence for a synapse-based model.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2007

Todd Richard D, Neuman Rosalind J

Abstract excerpt

To determine the mechanism of interaction of prenatal smoking exposure and child genotype in the development of attention deficit/hyperactivity disorder (ADHD), polymorphisms in the CHRNA4 gene were tested for interactions with prenatal smoking exposure on risk for ADHD subtypes using multiple logistic regression. An exon 5 polymorphism demonstrated a significant interaction with history of maternal smoking...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention Deficit Disorder with Hyperactivity
Share to Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pregnancy

Share to Prenatal Exposure Delayed Effects

Share to Receptors, Nicotinic

Share to Smoking

Share to Synapses

Source

Identifiers

PMID: 17955458
DOI: 10.1002/ajmg.b.30640

Genes

CHRNA4
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-environment interactions in the development of combined type ADHD: evidence for a synapse-based model.PMID 17955458Read ↗

Prenatal smoking exposure and dopaminergic genotypes interact to cause a severe ADHD subtype.Semantic proximity Read ↗

Gene-environment interactions in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

ADHD co-morbidities: A review of implication of gene × environment effects with dopamine-related genes.Semantic proximity Read ↗

ADHD and smoking: from genes to brain to behavior.Semantic proximity Read ↗

Interaction of dopamine transporter genotype with prenatal smoke exposure on ADHD symptoms.Semantic proximity Read ↗

Interactions between genotype and retrospective ADHD symptoms predict lifetime smoking risk in a sample of young adults.Semantic proximity Read ↗

Role of dopamine transporter genotype and maternal prenatal smoking in childhood hyperactive-impulsive, inattentive, and oppositional behaviors.Semantic proximity Read ↗

Effects of dopaminergic genes, prenatal adversities, and their interaction on attention-deficit/hyperactivity disorder and neural correlates of response inhibition.Semantic proximity Read ↗

The dopamine receptor D4 7-repeat allele and prenatal smoking in ADHD-affected children and their unaffected siblings: no gene-environment interaction.Semantic proximity Read ↗

Understanding genes, environment and their interaction in attention-deficit hyperactivity disorder: is there a role for neuroimaging?Semantic proximity Read ↗

Role of gene-gene/gene-environment interaction in the etiology of eastern Indian ADHD probands.Semantic proximity Read ↗

Molecular genetics of attention-deficit/hyperactivity disorder: an overview.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.