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Article

Regulation of growth differentiation factor 9 expression in oocytes in vivo: a key role of the E-box.

Biology of reproduction - 1 Jun 2006

Yan Changning, Elvin Julia A, Lin Yi-Nan, Hadsell Lou Ann, Wang Jie, DeMayo Francesco J, Matzuk Martin M

Abstract excerpt

Growth differentiation factor 9 (GDF9) is preferentially expressed in oocytes and is essential for female fertility. To identify regulatory elements that confer high-level expression of GDF9 in the ovary but repression in other tissues, we generated transgenic mice in which regions of the Gdf9 locus were fused to reporter genes. Two transgenes (-10.7/+5.6mGdf9-GFP) and (-3.3/+5.6mGdf9-GFP) that contained...

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Identifiers

PMID: 16495478
DOI: 10.1095/biolreprod.105.050013

Genes

GDF9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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