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Article

Mapping temporally varying quantitative trait loci in time-to-failure experiments.

Genetics - 1 Feb 2007

Johannes Frank

Abstract excerpt

Existing methods for mapping quantitative trait loci (QTL) in time-to-failure experiments assume that the QTL effect is constant over the course of the study. This assumption may be violated when the gene(s) underlying the QTL are up- or downregulated on a biologically meaningful timescale. In such situations, models that assume a constant effect can fail to detect QTL in a whole-genome scan. To investigate this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17151261
DOI: 10.1534/genetics.106.059808
PMCID: PMC1800607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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