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Article

Statistical optimization of parametric accelerated failure time model for mapping survival trait loci.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Mar 2011

Piao Zhongze, Zhou Xiaojing, Yan Li, Guo Ying, Yang Runqing, Luo Zhixiang, Prows Daniel R

Abstract excerpt

Most existing statistical methods for mapping quantitative trait loci (QTL) are not suitable for analyzing survival traits with a skewed distribution and censoring mechanism. As a result, researchers incorporate parametric and semi-parametric models of survival analysis into the framework of the interval mapping for QTL controlling survival traits. In survival analysis, accelerated failure time (AFT) model is...

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PMID: 21107519
DOI: 10.1007/s00122-010-1491-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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