Article
Dopamine transporter (DAT) genotype (VNTR) and phenotype in extrapyramidal symptoms induced by antipsychotics.
Schizophrenia research - 1 Feb 2007
Lafuente Amalia, Bernardo Miquel, Mas Sergi, Crescenti Anna, Aparici Monica, Gassó Patricia, Catalan Rosa, Mateos Jose J, Lomeña Francisco, Parellada Eduard
Abstract excerpt
INTRODUCTION: Impaired dopamine transporter (DAT) function may be involved in antipsychotic (AP)-induced extrapyramidal symptoms (EPS). A polymorphism involving a variable number of tandem repeats (VNTR) has been described in the DAT gene (SLC6A3). OBJECTIVE: We studied whether the SLC6A3 VNTR polymorphism is a risk or protection factor for AP-induced EPS. We also investigated the relationship between the...
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