Article
Association of susceptibility to brucellosis and interleukin-4 promoter polymorphism.
Scandinavian journal of infectious diseases - 1 Jan 2006
Rezazadeh Mehdi, Hajilooi Mehrdad, Haidari Mehran, Rafiei Alireza, Alavi Seyed Ahmad, Keramat Fariba
Abstract excerpt
A C-T substitution at position 590 in the interleukin-4 (IL-4) gene is associated with increased production of IL-4. We sought to determine the associations between this polymorphism and susceptibility to brucellosis. DNA was extracted from the whole blood of 163 control individuals and 282 patie...
Topics
- Adult
- Brucella
- Brucellosis
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-4
- Male
- Middle Aged
- Odds Ratio
- Polymorphism, Genetic
- Promoter Regions, Genetic
