Article
Association of susceptibility to brucellosis and interleukin-4 promoter polymorphism.
Scandinavian journal of infectious diseases - 1 Jan 2006
Rezazadeh Mehdi, Hajilooi Mehrdad, Haidari Mehran, Rafiei Alireza, Alavi Seyed Ahmad, Keramat Fariba
Abstract excerpt
A C-T substitution at position 590 in the interleukin-4 (IL-4) gene is associated with increased production of IL-4. We sought to determine the associations between this polymorphism and susceptibility to brucellosis. DNA was extracted from the whole blood of 163 control individuals and 282 patients with brucellosis. A polymorphism in the IL-4 gene at position 590 from the promoter site was determined using an...
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