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Article

Motor neuron disease in mice expressing the wild type-like D90A mutant superoxide dismutase-1.

Journal of neuropathology and experimental neurology - 1 Dec 2006

Jonsson P Andreas, Graffmo Karin S, Brännström Thomas, Nilsson Peter, Andersen Peter M, Marklund Stefan L

Abstract excerpt

Mutant human CuZn-superoxide dismutases (hSOD1s) cause amyotrophic lateral sclerosis (ALS). The most common mutation is the wild type-like D90A and to explore its properties, transgenic mice were generated and compared with mice expressing wild-type hSOD1. D90A hSOD1 was both in vivo in mice and...

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Identifiers

PMID: 17146286
DOI: 10.1097/01.jnen.0000248545.36046.3c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17146286-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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