Article
Mitochondriopathy in Parkinson Disease and Amyotrophic Lateral Sclerosis
1 Dec 2006
Abstract excerpt
The causes of the selective neurodegeneration in Parkinson disease (PD) and amyotrophic lateral sclerosis (ALS) are unknown and commonalities among these and other age-related neurodegenerative diseases continue to be sought. Morphologic, biochemical, molecular genetic, and cell/animal model studies suggest that mitochondria might be a convergence point for neurodegeneration. The functions and properties of...
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