Article
Mitochondria and neurodegeneration.
Bioscience reports - 1 Jun 2007
Petrozzi Lucia, Ricci Giulia, Giglioli Noemi J, Siciliano Gabriele, Mancuso Michelangelo
Abstract excerpt
Many lines of evidence suggest that mitochondria have a central role in ageing-related neurodegenerative diseases. However, despite the evidence of morphological, biochemical and molecular abnormalities in mitochondria in various tissues of patients with neurodegenerative disorders, the question "is mitochondrial dysfunction a necessary step in neurodegeneration?" is still unanswered. In this review, we highlight...
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