Article
Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence.
Cancer research - 1 Dec 2006
Kahl Philip, Gullotti Lucia, Heukamp Lukas Carl, Wolf Susanne, Friedrichs Nicolaus, Vorreuther Roland, Solleder Gerold, Bastian Patrick J, Ellinger Jörg, Metzger Eric, Schüle Roland, Buettner Reinhard
Abstract excerpt
Prostate cancer biology varies from locally confined tumors with low risk for relapse to tumors with high risk for progression even after radical prostatectomy. Currently, there are no reliable biomarkers to predict tumor relapse and poor clinical outcome. In this study, we correlated expression patterns of the androgen receptor (AR) coactivators lysine-specific histone demethylase 1 (LSD1) and four and a half...
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