Article
A pancreatic exocrine cell factor and AP4 bind overlapping sites in the amylase 2A enhancer.
Biochemistry - 20 Aug 1991
Fodor E, Weinrich S L, Meister A, Mermod N, Rutter W J
Abstract excerpt
A factor found in pancreatic exocrine cell lines and pancreatic nuclei binds selectively to the alpha-amylase 2A transcriptional enhancer. Pancreatic exocrine cell extracts protect asymmetrically an unusually large, 35 base pair region from DNase I digestion in vitro, suggesting the involvement o...
Topics
- Amylases
- Animals
- Base Sequence
- Cell Line
- Cricetinae
- DNA-Binding Proteins
- Dogs
- Enhancer Elements, Genetic
- Genes, Overlapping
- Insulinoma
- Molecular Sequence Data
- Mutation
- Pancreas
- Rats
- Simian virus 40
- Transcription Factors