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Article

The tissue-specific regulation of the carboxyl ester lipase gene in exocrine pancreas differs significantly between mouse and human.

The Biochemical journal - 15 Oct 2000

Kannius-Janson M, Lidberg U, Bjursell G, Nilsson J

Abstract excerpt

The carboxyl ester lipase (CEL) gene is highly expressed in exocrine pancreas and expression of the human CEL gene is mediated by a strong tissue-specific enhancer, which is absolutely necessary for high-level expression. The mouse promoter, on the other hand, does not contain a corresponding enhancer element, but instead is totally dependent on another pancreas-specific element. This element is identified as a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carboxylesterase

Share to Carboxylic Ester Hydrolases

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Source

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Identifiers

PMID: 11023822
PMCID: PMC1221372

Genes

CEL
EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The tissue-specific regulation of the carboxyl ester lipase gene in exocrine pancreas differs significantly between mouse and human.PMID 11023822Read ↗

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The Role of PTF1-P48 in Pancreatic Acinar Gene ExpressionSemantic proximity Read ↗

A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis.Semantic proximity Read ↗

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