Article
[Autoimmune-alloimmune neonatal neutropenia. Serum reactive IgG and neutrophil-specific phenotype detected by flow cytometry].
Medicina - 1 Jan 2006
Riera Norma E, Kantor Gustavo L, Khoury Marina, Nucci Rodrigo Parias, Rapetti Maria Cristina, Aixala Monica, Goldsztein Sofia, Flores Gabriela, de Bracco Maria M de E
Abstract excerpt
Auto or alloantibodies reactive with neutrophils define immune neutropenia. Alloimmune neonatal neutropenia is caused by maternal sensitization to paternal neutrophil antigens, resulting in IgG antibodies that are transferred to the fetus through the placenta. We present the studies in 4 children from 3 families with neutropenia of unknown origin (two of them were brothers). They were evaluated by flow cytometry...
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