Article
Innovative restriction site created PCR-RFLP for detection of benzimidazole resistance in Teladorsagia circumcincta.
Parasitology research - 1 Apr 2007
Shayan Parviz, Eslami Ali, Borji Hassan
Abstract excerpt
Benzimidazole compounds, especially albendazole, are the most commonly used anthelmintics for deworming of small ruminants in Iran. It is believed that the therapeutic effects of the benzimidazoles (BZs) come through their binding capacity to the beta-tubulin isotype 1. Substitution of phenylalanine to tyrosine at position 200 of this polypeptide confers resistance to BZs. Several investigators developed...
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