Association between HLA-DRB1*15 and Japanese patients with rheumatoid arthritis complicated by renal involvement.

doi:10.1159/000045273

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Article

Association between HLA-DRB1*15 and Japanese patients with rheumatoid arthritis complicated by renal involvement.

Nephron - 1 Feb 1999

Tokunaga N K, Noda R, Kaneoka H, Ogahara S, Murata T, Hiratsuka T, Michinaga I, Naito S

Abstract excerpt

We performed serological phenotyping of HLA antigens in 175 patients with rheumatoid arthritis (RA) with (n = 41) and without (n = 134) renal involvement (RI), and DNA typing of HLA class II alleles in 75 patients. Among the patients with RA, the frequency of serologically determined HLA-DR4 was found to be significantly increased (odds ratio: 1.8, confidence interval: 1.3-2.5, p = 2.4x10(-4)). In the patients...

Topics

Aged
Alleles
Arthritis, Rheumatoid
Asian People
Female
Genotype
HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Histocompatibility Testing
Humans
Japan
Kidney Diseases
Male
Middle Aged
Phenotype

Source

Open in PubMed

Identifiers

PMID: 9933752
DOI: 10.1159/000045273

Provenance

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