Article
[Study on the association of HLA-DR4 with IDDM susceptibility in a Chinese population].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Feb 1997
Qiu C, Liu Y, Zhou W, Zhu X
Abstract excerpt
HLA-DR4 and its subtypes were studied by PCP/SSP, PCR/SSOP, and PCR/RFLP methods in 81 patients with IDDM and 106 normal controls in the Han's nationality Chinese population. The results showed no difference in frequencies of DR4 between the IDDM group and the controls (21.0% vs 17.9%), but DRB1*0405, as a subtype Dw15, was significantly associated with IDDM susceptibility (58.8% vs 21.1%, RR = 2.67, P < 0.05)....
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