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Article

MHC-linked susceptibility to type 1 diabetes in the NOD mouse: further localization of Idd16 by subcongenic analysis.

Annals of the New York Academy of Sciences - 1 Oct 2006

Fujisawa Tomomi, Ikegami Hiroshi, Noso Shinsuke, Yamaji Kaori, Nojima Koji, Babaya Naru, Itoi-Babaya Michiko, Hiromine Yoshihisa, Kobayashi Misato, Makino Susumu, Ogihara Toshio

Abstract excerpt

Although major histocompatibility complex (MHC)-linked susceptibility is the strongest component, recent studies demonstrated that MHC-linked susceptibility to type 1 diabetes consists of multiple components both in humans and non-obese diabetic (NOD) mouse. In the NOD mouse, Idd16 has been mapped to the region adjacent to, but distinct from Idd1 in the MHC class II region. Establishment of subcongenic NOD.CTS-H2...

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PMID: 17130541
DOI: 10.1196/annals.1375.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MHC-linked susceptibility to type 1 diabetes in the NOD mouse: further localization of Idd16 by subcongenic analysis.PMID 17130541Read ↗

Congenic mapping of the MHC-linked susceptibility to type 1 diabetes in the NOD mouse: at least two genes contribute to the Idd16 effect.Semantic proximity Read ↗

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