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Article

Molecular basis for differential nucleotide binding of the nucleotide-binding domain of ABC-transporter CvaB.

Biochemistry - 5 Dec 2006

Guo Xiangxue, Chen Xianfeng, Weber Irene T, Harrison Robert W, Tai Phang C

Abstract excerpt

The cytoplasmic membrane protein CvaB, involved in colicin V secretion in Escherichia coli, belongs to the ABC-transporter family in which ATP hydrolysis is typically the driving force for substrate transport. However, our previous studies indicated that the nucleotide-binding domain of CvaB could also bind and hydrolyze GTP and, indeed, highly preferred GTP over ATP at low temperatures. In this study, we have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17128986
DOI: 10.1021/bi061506i
PMCID: PMC2515628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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