Recent evolutionary origin of the expression of the glial fibrillary acidic protein (GFAP) in lens epithelial cells. A molecular and genetic analysis of various mouse species.

doi:10.1016/0169-328x(91)90106-8

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Article

Recent evolutionary origin of the expression of the glial fibrillary acidic protein (GFAP) in lens epithelial cells. A molecular and genetic analysis of various mouse species.

Brain research. Molecular brain research - 1 May 1991

Boyer S, Montagutelli X, Gomès D, Simon-Chazottes D, Guénet J L, Dupouey P

Abstract excerpt

We have investigated the phylogenetic distribution of the glial fibrillary acidic protein (GFAP) in lens epithelial cells (LEC) of various mouse species within the genus Mus. We have shown that lens GFAP is expressed in mice of the Mus musculus complex and in Mus spicilegus and Mus macedonicus species (L.GFAP(+) phenotype) while it is absent in Mus spretus, Mus caroli and Mus cooki species (L.GFAP(-) phenotype)....

Topics

Animals
Biological Evolution
Blotting, Northern
Blotting, Southern
Chromosome Mapping
DNA
DNA Probes
Epithelial Cells
Epithelium
Glial Fibrillary Acidic Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunohistochemistry

Lens, Crystalline

Mice

Muridae

Phenotype

RNA

Species Specificity

Source

Open in PubMed

Identifiers

PMID: 1712888
DOI: 10.1016/0169-328x(91)90106-8

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1712888-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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