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Article

EGF and FGF-2 infusion increases post-ischemic neural progenitor cell proliferation in the adult rat brain.

Neurosurgery - 1 Dec 2005

Türeyen Kudret, Vemuganti Raghu, Bowen Kellie K, Sailor Kurt A, Dempsey Robert J

Abstract excerpt

OBJECTIVE: Epidermal growth factor (EGF) and fibroblast growth factor-2 (FGF-2) play a critical role in neurogenesis. In the present study, we evaluated the additive effect of administering these two factors on post-ischemic progenitor cell proliferation, survival, and phenotypic maturation in the hippocampal dentate gyrus (DG) and the subventricular zone (SVZ) in the adult rat brain after transient middle...

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Source

Identifiers

PMID: 16331174
DOI: 10.1227/01.neu.0000186040.96929.8a

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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