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Article

Endothelial Nitric Oxide Synthase (Glu298Asp) Polymorphism is Associated Significantly with Ischemic Stroke Presenting with Seizures and Altered Sensorium.

Neurology India - 1 Jan 2000

Saluja Alvee, Saraswathy Kallur N, Thakur Sunil, Margekar Shubhalaxmi, Goyal Ankit, Dhamija Rajinder K

Abstract excerpt

BACKGROUND: Endothelial nitric oxide synthase (eNOS) is an enzymatic marker whose genetic polymorphism might predispose to acute ischemic stroke (AIS) via vascular endothelial dysfunction. It has a potential role in atherosclerosis, making it a plausible risk factor for stroke. Prior studies have failed to prove a conclusive relationship between eNOS polymorphism and AIS. OBJECTIVE: The aim of this study is to...

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PMID: 34169869
DOI: 10.4103/0028-3886.319217

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