Article
Expression of Integrin beta3 is correlated to the properties of quiescent hemopoietic stem cells possessing the side population phenotype.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2006
Umemoto Terumasa, Yamato Masayuki, Shiratsuchi Yoshiko, Terasawa Masao, Yang Joseph, Nishida Kohji, Kobayashi Yoshiro, Okano Teruo
Abstract excerpt
With significant attention paid to the field of tissue-specific stem cells, the identification of stem cell-specific markers is of considerable importance. Previously, the side population (SP) phenotype, with the capacity to efflux the DNA-binding dye Hoechst 33342, has been recognized as a common feature of adult tissue-specific stem cells. In this study, we show that high expression of integrin beta(3) (CD61)...
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