Article
fliP influences Citrobacter koseri macrophage uptake, cytokine expression and brain abscess formation in the neonatal rat.
Journal of medical microbiology - 1 Dec 2006
Townsend Stacy M, Gonzalez-Gomez Ignacio, Badger Julie L
Abstract excerpt
Citrobacter koseri causes neonatal meningitis frequently complicated with multiple brain abscesses. During C. koseri central nervous system infection in the neonatal rat model, previous studies have documented many bacteria-filled macrophages within the neonatal rat brain and abscesses. Previous studies have also shown that C. koseri is taken up by, survives phagolysosomal fusion and replicates in macrophages in...
Topics
- Adaptation, Physiological
- Animals
- Animals, Suckling
- Bacterial Proteins
- Brain
- Brain Abscess
- Citrobacter koseri
- Cytokines
- DNA Transposable Elements
- Enterobacteriaceae Infections
- Flagella
- Green Fluorescent Proteins
- Humans
- Inflammation
- Macrophages
- Molecular Sequence Data
- Mutation
- Rats