Article
Diversity of Ca2+-activated K+ channel transcripts in inner ear hair cells.
Gene - 15 Jan 2007
Beisel Kirk W, Rocha-Sanchez Sonia M, Ziegenbein Sylvia J, Morris Ken A, Kai Chikatoshi, Kawai Jun, Carninci Piero, Hayashizaki Yoshihide, Davis Robin L
Abstract excerpt
Hair cells express a complement of ion channels, representing shared and distinct channels that confer distinct electrophysiological signatures for each cell. This diversity is generated by the use of alternative splicing in the alpha subunit, formation of heterotetrameric channels, and combinatorial association with beta subunits. These channels are thought to play a role in the tonotopic gradient observed in...
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