Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal analysis favours a monoclonal origin for serous borderline tumours with peritoneal implants.

The Journal of pathology - 1 Dec 2006

Sieben N L, Roemen G M J M, Oosting J, Fleuren G J, van Engeland M, Prat J

Abstract excerpt

Serous borderline tumours (SBTs) of the ovary were originally classified as such because the vast majority behave in a remarkably indolent manner, even in the presence of widespread tumour deposits, termed implants, and/or lymph node involvement. The pathogenesis of the implants is currently unknown. Two major hypotheses have been proposed: the first favours a monoclonal origin, arguing that the peritoneal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, ras
Share to Loss of Heterozygosity
Share to Neoplasm Invasiveness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Staging

Share to Ovarian Neoplasms

Share to Peritoneal Neoplasms

Share to Peritoneum

Share to Proto-Oncogene Proteins B-raf

Source

Identifiers

PMID: 17096315
DOI: 10.1002/path.2074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal analysis favours a monoclonal origin for serous borderline tumours with peritoneal implants.PMID 17096315Read ↗

KRAS, BRAF genotyping reveals genetic heterogeneity of ovarian borderline tumors and associated implants.Semantic proximity Read ↗

Mitochondrial DNA sequencing demonstrates clonality of peritoneal implants of borderline ovarian tumorsSemantic proximity Read ↗

Mutational analysis of BRAF and KRAS in ovarian serous borderline (atypical proliferative) tumours and associated peritoneal implants.Semantic proximity Read ↗

Comprehensive genomic profiling reveals ubiquitous KRAS mutations and frequent PIK3CA mutations in ovarian seromucinous borderline tumor.Semantic proximity Read ↗

Adenocarcinoma of Mullerian origin: review of pathogenesis, molecular biology, and emerging treatment paradigmsSemantic proximity Read ↗

Serous borderline tumours of the ovary.Semantic proximity Read ↗

Synchronous endometrioid endometrial and ovarian carcinomas are biologically related: A clinico‑pathological and molecular (next generation sequencing) study of 22�casesSemantic proximity Read ↗

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.Semantic proximity Read ↗

Molecular evidence for a clonal relationship between synchronous uterine endometrioid carcinoma and ovarian clear cell carcinoma: a new example of "precursor escape"?Semantic proximity Read ↗

Clonality, Heterogeneity, and Evolution of Synchronous Bilateral Ovarian Cancer.Semantic proximity Read ↗

The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory.Semantic proximity Read ↗

Pathogenesis of ovarian cancer: lessons from morphology and molecular biology and their clinical implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.