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Article

The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory.

The American journal of surgical pathology - 1 Mar 2010

Kurman Robert J, Shih Ie-Ming

Abstract excerpt

Ovarian cancer is the most lethal gynecologic malignancy. Efforts at early detection and new therapeutic approaches to reduce mortality have been largely unsuccessful, because the origin and pathogenesis of epithelial ovarian cancer are poorly understood. Despite numerous studies that have carefully scrutinized the ovaries for precursor lesions, none have been found. This has led to the proposal that ovarian...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20154587
DOI: 10.1097/PAS.0b013e3181cf3d79
PMCID: PMC2841791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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