Article
Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients.
Gut - 1 Jan 2002
Katballe N, Christensen M, Wikman F P, Ørntoft T F, Laurberg S
Abstract excerpt
BACKGROUND: Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant cancer syndrome, characterised by familial aggregation of HNPCC related cancers, germline mutations in mismatch repair genes, and/or microsatellite instability (MSI) in tumour tissue. AIM: To estimate the frequency of HNPCC among non-selected Danish patients with colorectal cancer (CRC), and to evaluate the value of MSI...
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