Article
Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment.
Proceedings of the National Academy of Sciences of the United States of America - 21 Nov 2006
Blankenfeldt Wulf, Thomä Nicolas H, Wray John S, Gautel Mathias, Schlichting Ilme
Abstract excerpt
Myosin II is the major component of the muscle thick filament. It consists of two N-terminal S1 subfragments ("heads") connected to a long dimeric coiled-coil rod. The rod is in itself twofold symmetric, but in the filament, the two heads point away from the filament surface and are therefore not...
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