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Article

Structural diversity in the atomic resolution 3D fingerprint of the titin M-band segment.

PloS one - 1 Jan 2019

Chatziefthimiou Spyros D, Hornburg Philipp, Sauer Florian, Mueller Simone, Ugurlar Deniz, Xu Emma-Ruoqi, Wilmanns Matthias

Abstract excerpt

In striated muscles, molecular filaments are largely composed of long protein chains with extensive arrays of identically folded domains, referred to as "beads-on-a-string". It remains a largely unresolved question how these domains have developed a unique molecular profile such that each carries out a distinct function without false-positive readout. This study focuses on the M-band segment of the sarcomeric...

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Identifiers

PMID: 31856237
DOI: 10.1371/journal.pone.0226693
PMCID: PMC6922384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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