Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer

31 Oct 2006

Abstract excerpt

The gene SASH1 (SAM- and SH3-domain containing 1) has originally been identified as a candidate tumour suppressor gene in breast cancer. SASH1 is a member of the SH3-domain containing expressed in lymphocytes (SLY1) gene family that encodes signal adapter proteins composed of several protein-protein interaction domains. The other members of this family are expressed mainly in haematopoietic cells, whereas SASH1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Genetic factors in colorectal cancer
Share to RNA and protein synthesis mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17088907
DOI: 10.1038/sj.bjc.6603452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancerPMID 17088907Read ↗

The candidate tumor suppressor SASH1 interacts with the actin cytoskeleton and stimulates cell-matrix adhesion.Semantic proximity Read ↗

Lack of somatic mutation in the coding sequence of SIAH1 in tumors hemizygous for this candidate tumor suppressor gene.Semantic proximity Read ↗

The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial–Mesenchymal Transition and Metastasis in Colorectal CancerSemantic proximity Read ↗

Transcriptional Regulation and Biological Functions of Selenium-Binding Protein 1 in Colorectal Cancer In Vitro and in Nude Mouse XenograftsSemantic proximity Read ↗

S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesisSemantic proximity Read ↗

Down-Regulation of CDH1 Is Associated with Expression of SNAI1 in Colorectal AdenomasSemantic proximity Read ↗

Human Sgo1 downregulation leads to chromosomal instability in colorectal cancerSemantic proximity Read ↗

HLTF gene silencing in human colon cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.