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Article

Variability of voriconazole plasma levels measured by new high-performance liquid chromatography and bioassay methods.

Antimicrobial agents and chemotherapy - 1 Jan 2007

Pascual Andres, Nieth Valérie, Calandra Thierry, Bille Jacques, Bolay Saskia, Decosterd Laurent A, Buclin Thierry, Majcherczyk Paul A, Sanglard Dominique, Marchetti Oscar

Abstract excerpt

Voriconazole (VRC) is a broad-spectrum antifungal triazole with nonlinear pharmacokinetics. The utility of measurement of voriconazole blood levels for optimizing therapy is a matter of debate. Available high-performance liquid chromatography (HPLC) and bioassay methods are technically complex, time-consuming, or have a narrow analytical range. Objectives of the present study were to develop new, simple...

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Identifiers

PMID: 17088483
DOI: 10.1128/AAC.00957-06
PMCID: PMC1797701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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