Article
Therapeutic drug monitoring of voriconazole.
Therapeutic drug monitoring - 1 Aug 2008
Brüggemann Roger J M, Donnelly J Peter, Aarnoutse Rob E, Warris Adilia, Blijlevens Nicole M A, Mouton Johan W, Verweij Paul E, Burger David M
Abstract excerpt
Voriconazole is a triazole antifungal developed for the treatment of life-threatening fungal infections in immunocompromised patients. The drug, which is available for both oral and intravenous administration, has broad-spectrum activity against pathogenic yeasts, dimorphic fungi, and opportunistic molds. Voriconazole has a nonlinear pharmacokinetic profile with a wide inter- and intraindividual variety. This...
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