Article
Monitoring trough voriconazole plasma concentrations in haematological patients: real life multicentre experience.
Mycoses - 1 Nov 2012
Racil Zdenek, Winterova Jana, Kouba Michal, Zak Pavel, Malaskova Ludmila, Buresova Lucie, Toskova Martina, Lengerova Martina, Kocmanova Iva, Weinbergerova Barbora, Timilsina Shira, Rolencova Monika, Cetkovsky Petr, Mayer Jiri
Abstract excerpt
The objective of this retrospective study was to evaluate results from voriconazole therapeutic drug monitoring (TDM) in haematological patients in routine clinical practice. Between 2005 and 2010, 1228 blood samples were obtained from 264 haematological patients (median 3 samples/patient; range 1-27) receiving voriconazole for targeted/preemptive treatment of invasive aspergillosis (IA) (46.3% of samples),...
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