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Article

DJ-1: A New Comer in Parkinsons Disease Pathology

1 Nov 2007

Abstract excerpt

Parkinson's disease (PD) is a movement disorder of high prevalence in the elderly. It is characterized by a loss of dopaminergic neurons and the presence of intracytoplasmic inclusions named Lewy bodies. To date six familial PD-associated proteins have been identified so far. Some of them are implicated in the development of either autosomal dominant (alpha-synuclein and LRRK2 (leucine-rich repeat kinase...

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PMID: 18045143
DOI: 10.2174/156652407782564426

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