Article
RecO is essential for DNA damage repair in Deinococcus radiodurans.
Journal of bacteriology - 1 Apr 2008
Xu Guangzhi, Wang Liangyan, Chen Huan, Lu Huiming, Ying Nanjiao, Tian Bing, Hua Yuejin
Abstract excerpt
Here we present direct evidence for the vital role of RecO in Deinococcus radiodurans's radioresistance. A recO null mutant was constructed using a deletion replacement method. The mutant exhibited a growth defect and extreme sensitivity to irradiation with gamma rays and UV light. These results suggest that DNA repair in this organism occurs mainly via the RecF pathway.
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