Article
[Construction of the recQ double mutants and analysis of adversity in Deinococcus radiodurans].
Wei sheng wu xue bao = Acta microbiologica Sinica - 1 Apr 2006
Huang Li-Fen, Zhang Shao-Wen, Hua Xiao-Ting, Gao Guan-Jun, Hua Yue-Jin
Abstract excerpt
As a subfamily member of SF1 superfamily, the RecO helicases are highly conserved in evolution and are required for maintaining genome stability in all organisms. Loss of RecO helicase function leads to a breakdown in the maintenance of genome integrity, in particular hyper-recombination. Named after the recQ gene of Escherichia coli, lower eukaryotic species generally only contain a single RecQ family...
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