Article
Mutational analysis of betaglycan/TGF-betaRIII in premature ovarian failure.
Fertility and sterility - 1 Jan 2007
Chand Ashwini L, Robertson David M, Shelling Andrew N, Harrison Craig A
Abstract excerpt
Targeted mutational screening of the inhibin-binding domain of betaglycan (exons 11 and 12) demonstrated an increased occurrence of the exon 12 194969T-->C variant in POF patients (27/54; 50%) compared to controls (8/41; 19.5%; P=.002); however, no gene variations were identified in exon 11.
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