RNase E, an endoribonuclease, has a general role in the chemical decay of Escherichia coli mRNA: evidence that rne and ams are the same genetic locus.

doi:10.1111/j.1365-2958.1990.tb00574.x

Article

RNase E, an endoribonuclease, has a general role in the chemical decay of Escherichia coli mRNA: evidence that rne and ams are the same genetic locus.

Molecular microbiology - 1 Dec 1990

Mudd E A, Krisch H M, Higgins C F

Abstract excerpt

Escherichia coli RNase E is known to process RNA precursors at specific sites. We show that this endoribonuclease has a general role in E. coli mRNA turnover and affects the stability of specific transcripts. The effect of the rne mutation on functional stability of mRNA was much less pronounced...

Topics

Cloning, Molecular
Endoribonucleases
Escherichia coli
Gene Expression
Genes, Bacterial
Half-Life
Kinetics
Mutation
Phenotype
RNA, Bacterial
RNA, Messenger
RNA, Ribosomal
Restriction Mapping
Transcription, Genetic

RNase E, an endoribonuclease, has a general role in the chemical decay of Escherichia coli mRNA: evidence that rne and ams are the same genetic locus.

Abstract excerpt

Topics

Discuss the evidence