Article
RNase G of Escherichia coli exhibits only limited functional overlap with its essential homologue, RNase E.
Molecular microbiology - 1 Aug 2003
Ow Maria C, Perwez Tariq, Kushner Sidney R
Abstract excerpt
RNase G (rng) is an E. coli endoribonuclease that is homologous to the catalytic domain of RNase E (rne), an essential protein that is a major participant in tRNA maturation, mRNA decay, rRNA processing and M1 RNA processing. We demonstrate here that whereas RNase G inefficiently participates in the degradation of mRNAs and the processing of 9S rRNA, it is not involved in either tRNA or M1 RNA processing. This...
Topics
- Alleles
- Catalytic Domain
- Endoribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Genetic Complementation Test
- Half-Life
- Protein Subunits
- RNA Processing, Post-Transcriptional
- RNA, Bacterial
- RNA, Catalytic
- RNA, Messenger
- RNA, Ribosomal
- RNA, Transfer
- Recombinant Fusion Proteins
- Ribonuclease P
- Sequence Homology, Amino Acid