Article
The cumate gene-switch: a system for regulated expression in mammalian cells.
BMC biotechnology - 3 Nov 2006
Mullick Alaka, Xu Yan, Warren René, Koutroumanis Maria, Guilbault Claire, Broussau Sophie, Malenfant Félix, Bourget Lucie, Lamoureux Linda, Lo Rita, Caron Antoine W, Pilotte Amelie, Massie Bernard
Abstract excerpt
BACKGROUND: A number of expression systems have been developed where transgene expression can be regulated. They all have specific characteristics making them more suitable for certain applications than for others. Since some applications require the regulation of several genes, there is a need for a variety of independent yet compatible systems. RESULTS: We have used the regulatory mechanisms of bacterial...
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