Article
Signal Transduction Pathways Controlling the Switch Between Keratinocyte Growth and Differentiation
1 Jul 1999
Abstract excerpt
Self-renewing epithelia are characterized by a high turnover rate and a fine balance between growth and differentiation. Such a balance is influenced by many exogenous factors, including gradients of diffusible molecules, cell/substrate adhesion contacts, and direct cell-cell communication. The inter-connection between these various extracellular signals and underlying intracellular pathways is clearly of great...
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